当センターでは、さまざまな研究に取り組んでいます。その一部を紹介します。
大学病院の特色といえる大規模な調査研究、そして生殖医療全般を扱う最先端の医療現場の特性を生かし、新しい治療法やよりよい医療の確立など、今後の医療への貢献を目指して、継続して研究に取り組んでまいります。
臨床研究に関するお知らせ
臨床研究に関するお知らせ
現在取り組んでいる研究
- 器官培養による精子形成に関する研究
- 小児がん患者の妊孕性温存を目指した精巣凍結法の開発に関する研究
- マウス卵活性化試験(MOAT)を用いたヒト精子の加齢性変化の研究
- 精巣腫瘍患者における精子形成能に関する研究
- 精子運動解析装置を用いた精液所見の日内変動の検討
- 炎症性腸疾患と造精機能の関係についての研究
- MRI を用いた射精機能の評価に関する研究
- 精液中酸化還元電位に関する研究
- 思春期前若年男児に対する精巣凍結保存に関する研究 同意説明文書のダウンロード
最近の学会発表(海外発表のみ)
- Iwahata T, Shin T, Shimomura Y, Suzuki K, Kobayashi T, Miyata A, Okada H: Outcome of testicular sperm extraction in 52 spinal cord injured-men. The 71st Annual Meeting of the American Society for Reproductive Medicine, Baltimore, 2015, 10
- Shin T, Iwahata T, Kobayashi T, Miyata A, Kobori Y, Okada H: Microdissection testicular extraction in post-chemotherapy patients. The 71st Annual Meeting of the American Society for Reproductive Medicine, Baltimore, 2015, 10.
- Shin T, Fukushima M, Shimomura Y, Suzuki K, Iwahata T, Miyata A, Okada H: Vitrification using dimethyl sulfoxide free cryoprotectant is a promising cryopreservation method for fertility preservation of immature mouse testicular tissue. The 31st Annual Meeting of European Society of Human Reproduction and Embryology, Lisbon, 2015, 6.
- Suzuki K, Shimomura Y, Iwahata T, Shin T, Okada H: Spermatogenesis of tumor-bearing testes in germ cell testicular cancer patients. The 2015 Annual Meeting of the American Urological Association, New Orleans, 2015, 5.
- Shin T, Fukushima M, Shimomura Y, Iwahata T, Suzuki K, Kobori Y, Okada H: Age does matter in sperm function to activate oocytes in subfertile men. The 70th Annual Meeting of the American Society for Reproductive Medicine, Hawaii, 2014, 10.
- Shin T, Fukushima M, Shimomura Y, Iwahata T, Suzuki K, Okada H: Inflammatory bowel disease and male infertility: a retrospective single-center study in Japan. The 70th Annual Meeting of the American Society for Reproductive Medicine, Hawaii, 2014, 10.
- Shin T, Fukushima M, Iwahata T, Suzuki K, Sadaoka Y, Ota S, Iijima M, Sato R, Nishio K, Kawaguchi M, Kobori Y, Ashizawa Y, Yagi H, Soh S, Arai G, Okada H: Oocyte activating ability of spermatozoa appears to decrease with aging among subfertile patients. The 2014 Annual Meeting of the American Urological Association, Orlando, 2014, 5.
最近の論文(欧文のみ)
- Shin T, Kobayashi T, Shimomura Y, Iwahata T, Suzuki K, Tanaka T, Fukushima M, Kurihara M, Miyata A, Kobori Y, Okada H. Microdissection testicular sperm extraction in Japanese patients with persistent azoospermia after chemotherapy. Int J Clin Oncol. 2016 Jun 15. [Epub ahead of print]
- Shin T, Okada H. Infertility in men with inflammatory bowel disease. World J Gastrointest Pharmacol Ther. 7(3):361-9. Published online Aug 6, 2016.
- Suzuki K, Shin T, Shimomura Y, Iwahata T, Okada H. Spermatogenesis in tumor-bearing testes in germ cell testicular cancer patients. Hum Reprod. [2015 Dec;30(12):2853-8.]
- Shin T, Iwahata T, Kobori Y, Kido Y, Soh S, Okada H. Chromosomal abnormalities in 1354 Japanese patients with azoospermia due to spermatogenic dysfunction. Int J Urol. [2016 Jan;23:188-9.]
- Kobori Y, Suzuki K, Iwahata T, Shin T, Sato R, Nishio K, Yagi H, Arai G, Soh S, Okada H. Induction of spermatogenesis by rhFSH for azoospermia due to spermatogenic dysfunction with maturation arrest: five case series. Syst Biol Reprod Med. [2015 Jun;61(3):168-70.]
- Kobori Y, Suzuki K, Iwahata T, Shin T, Sato R, Nishio K, Yagi H, Arai G, Soh S, Okada H. Hormonal therapy (hCG and rhFSH) for infertile men with adult-onset idiopathic hypogonadotropic hypogonadism. Syst Biol Reprod Med. 2015 Apr;61(2):110-2.
- Shin T, Kobori Y, Suzuki K, Iwahata T, Yagi H, Soh S, Arai G, Okada H. Inflammatory bowel disease in subfertile men and the effect of mesalazine on fertility. Syst Biol Reprod Med. 2014 Dec;60(6):373-6.