研究実績

2022

Ishii J, Sato-Yazawa H, Kashiwagi K, Nakadate K, Iwamoto M, Kohno K, Miyata-Hiramatsu C, Masawa M, Onozaki M, Noda S, Miyazawa T, Takagi M, Yazawa T: Endocrine secretory granule production is caused by a lack of REST and intragranular secretory content and accelerated by PROX1. J Mol Histol 53: 437-448, 2022.
Masawa M, Sato-Yazawa H, Kashiwagi K, Ishii J, Miyata-Hiramatsu C, Iwamoto M, Kohno K, Miyazawa T, Onozaki M, Noda S, Shimizu Y, Niho S, Yazawa T: REST Inactivation and Coexpression of ASCL1 and POU3F4 Are Necessary for the Complete Transformation of RB1/TP53-Inactivated Lung Adenocarcinoma into Neuroendocrine Carcinoma. Am J Pathol 192: 847-861, 2022.
Kashiwagi K, Sato-Yazawa H, Ishii J, Kohno K, Tatsuta I, Miyazawa T, Takagi M, Chiba H, Yazawa T: LXRβ Activation Inhibits the Proliferation of Small-cell Lung Cancer Cells by Depleting Cellular Cholesterol. Anticancer Res 42: 2923-2930, 2022.
Yamaguchi K, Yazawa T: Development of the human perihypoglossal nuclei from mid-gestation to the perinatal period: A morphological study. Neurosci Lett 782:136696, 2022.

2021

Kojima M, Sugimoto K, Kobayashi M, Ichikawa-Tomikawa N, Kashiwagi K, Watanabe T, Soeda S, Fujimori K, Chiba H: Aberrant claudin-6-adhesion signaling promotes endometrial cancer progression via estrogen receptor α. Mol Cancer Res 19:1208-1220, 2021.
Matsudera S, Sato-Yazawa H, Terada M, Yamaguchi T, Tani Y, Watanabe S, Kashiwagi K, Ishii J, Ito Y, Ogino K, Okamoto K, Nakajima M, Morita S, Yamaguchi S, Kuroda H, Tsuchioka T, Kojima K, Yazawa T: Histopathological evaluation of the effectiveness of oral Eppikajutsuto treatment for lymphatic malformation. J Pediatr Surg 56:1668-1672, 2021.
石井　順(分担執筆, 2021年3月)。原発性甲状腺機能低下症(甲状腺腫性) - SLC26A7異常症。深田修司総編集。遺伝子甲状腺疾患のすべて。日本医事新報社、197〜202頁、338〜339頁。

2020

Yamaguchi K: Development of the human accessory olivary nuclei: A morphometric and computerized 3D-reconstruction study. Neurosci Lett 721: 134816, 2020.
Tamada N, Tojo K, Yazawa T, Goto T: Necrosis rather than apoptosis is the dominant form of alveolar epithelial cell death in lipopolysaccharide-induced experimental acute respiratory distress syndrome model. Shock 54:128-139, 2020.

2019

Sugimoto K, Ichikawa-Tomikawa N, Kashiwagi K, Endo C, Tanaka S, Sawada N, Watabe T, Higashi T, Chiba H: Cell adhesion signals regulate the nuclear receptor activity. Proc Natl Acad Sci USA 116(49):24600-24609, 2019.
Yamaguchi K: Development of the human principal inferior olivary nucleus: A morphometric and computerized 3D-reconstruction study. Neurosci Lett 707, 134302, 2019.
Ishii J, Suzuki A, Kimura T, Tateyama M, Tanaka T, Yazawa T, Arimasu Y, Chen IS, Aoyama K, Kubo Y, Saitoh S, Mizuno H, Kamma H: Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7. Commun Biol 2:270, 2019.

2018

Nakashima Y, Morita R, Ui A, Iihara K, Yazawa T: Epithelial-myoepithelial carcinoma of the lung: a case report. Surgical Case Reports 4: 74, 2018.
Tojo K, Yoshida T, Yazawa T, Goto T: Driving-pressure-independent effects of open lung approach against experimental acute respiratory distress syndrome. Crit Care 22: 228, 2018.
Yamaguchi K: Development of the human lateral geniculate nucleus: A morphometric and computerized 3D-reconstruction study. Neurosci Lett 676: 1-7, 2018.
Tojo K, Tamada N, Nagamine Y, Yazawa T, Ota S, Goto T: Enhancement of glycolysis by inhibition of oxygen-sensing prolyl hydroxylases protects alveolar epithelial cells from acute lung injury. FASEB J 2018 (in press).
Kashiwagi K, Yanagida M, Matsui D, Tanaka M, Sugimoto K, Chen H, Ichikawa-Tomikawa N, Marubashi S, Suzuki H, Chiba H: Expression of liver X receptors in normal and refractory carcinoma tissues of the human lung and pancreas. Histol Histopathol 33: 497-505, 2018.

2017

Nishiura K, Ichikawa-Tomikawa N, Sugimoto K, Kunii Y, Kashiwagi K, Tanaka M, Yokoyama Y, Hino M, Sugino T, Yabe H, Takahashi H, Kakita A, Imura T, Chiba H: PKA activation and endothelial claudin-5 breakdown in the schizophrenic prefrontal cortex. Oncotarget 8: 93382-93391, 2017.
Yamamoto H, Ishii J, Chiba T, Nakazato Y, Hirano K, Kamma H: Sporadic minute medullary thyroid carcinoma with a double RET mutation: A case report. Pathol Int 67: 580-584, 2017.
Sawa A, Chiba T, Ishii J, Yamamoto H, Hara H, Kamma H: Effects of sorafenib and an adenylyl cyclase activator on in vitro growth of well-differentiated thyroid cancer cells. Endocr J 64: 1115-1123, 2017.
Oki H, Yazawa T, Baba Y, Kanegae Y, Sato H, Sakamoto S, Goto T, Saito I, Kurahashi K: Adenovirus vector expressing keratinocyte growth factor using CAG promoter impairs pulmonary function of mice with elastase-induced emphysema. Microbiol Immunol 61: 264-271, 2017.
Matsushima J, Yazawa T, Suzuki M, Takahashi Y, Ota S, Nakajima T, Yoshino I, Yokose T, Inoue T, Kawahara K, Nakatani Y: Clinicopathological, immunohistochemical and mutatation analyses of pulmonary enteric adenocarcinoma: Usefulness of SATB2 and b-catenin immunostaining for differentiation from metastatic colorectal carcinoma. Hum Pathol 64: 179-185, 2017.
Kigasawa H, Fujiwara M, Ishii J, Chiba T, Terado Y, Shimoyamada H, Mochizuki M, Kitamura O, Kamma H, Ohkura Y: Altered expression of cytokeratin 7 and CD117 in transitional mucosa adjacent to human colorectal cancer. Oncol Lett 14: 119-126, 2017.
Suzuki M, Matsushima J, Yazawa T, Ota S, Kiyokawa T, Sonehara H, Hanawa S, Mitsuhashi A, Shouzu M, Nakatani Y: A case of ovarian steroid cell tumor with bizarre nuclear atypical and CTNNB1 mutation. Pathol Int 67: 278-279, 2017.

2016

Nagamine Y, Tojo K, Yazawa T, Takaki S, Baba Y, Goto T, Kurahashi K: Inhibition of prolyl hydroxylase attenuates fas ligand-induced apoptosis and lung injury in mice. Am J Respir Cell Mol Biol 55: 878-888, 2016.
Ota S, Yazawa T, Tojo K, Baba Y, Uchiyama M, Goto T, Kurahashi K: Adrenaline aggravates lung injury caused by liver ischemia-reperfusion and high-tidal volume ventilation in rats. J Intensive Care 4: 8, 2016.
Koji H, Yazawa T, Nakabayashi K, Fujioka Y, Kamma H, Yamada A: CD8-positive T-cell lymphoproliferative disorder associated with Epstein-Barr virus-infected B-cells in a rheumatoid arthritis patient under methotrexate treatment. Mod Rheumatol 26: 271-275, 2016.
Ishii J, Yazawa T, Chiba T, Shishido-Hara Y, Arimasu Y, Sato H, Kamma H: PROX1 promotes secretory granule formation in medullary thyroid cancer cells. Endocrinology 157: 1289-1298, 2016.

2015

Yazawa T: Recent advances in histogenesis research of lung neuroendocrine cancers: Evidence obtained from functional analyses of primitive neural/neuroendocrine cell-specific transcription factors. Pathol Int 65: 277-285, 2015.
Yokoi H, Yazawa T, Matsumoto Y, Ikeda T, Ohkura Y, Kohno N, Fujiwara M: A case of an inflammatory pseudotumor that advanced to the maxillary sinus and orbital cavity, with the left pterygopalatine fossa as a principal site. Case Rep Otolaryngol 2015: 950823, 2015.
Suzuki M, Yazawa T, Ota S, Morimoto J, Yoshino I, Yamanaka S, Inayama Y, Kawabata Y, Shimizu Y, Komatsu M, Notohara K, Koda K, Nakatani Y: High-grade fetal adenocarcinoma of the lung is a tumour with a fetal phenotype that shows diverse differentiation, including high-grade neuroendocrine carcinoma: a clinicopathological, immunohistochemical and mutational study of 20 cases. Histopathology 67: 806-816, 2015.
Tojo K, Nagamine Y, Yazawa T, Mihara T, Baba Y, Ota S, Goto T, Kurahashi K: Atelectasis causes alveolar hypoxia-induced inflammation during uneven mechanical ventilation in rats. Intensive Care Medicine Experimental 3: 56, 2015.
Kaneko T, Kanno C, Ichikawa-Tomikawa N, Kashiwagi K, Yaginuma N, Ohkoshi C, Tanaka M, Sugino T, Imura T, Hasegawa H, Chiba H. Liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression. Oncotarget 6: 33345-33357, 2015.
Uchiyama M, Tojo K, Yazawa T, Ota S, Goto T, Kurahashi K: Edaravone prevents lung injury induced by hepatic ischemia-reperfusion. J Surg Res 194: 551-557, 2015.

2014

Tanaka K, Tanigaki S, Matsushima M, Miyazaki N, Hashimoto R, Izawa T, Sakai K, Yazawa T, Iwashita M: Prenatal diagnosis of umbilical artery thrombosis. Fetal Diagn Ther 35: 148-150, 2014.
Yazawa T: POU3F2 (POU class 3 homeobox 2). Atlas of Genetics and Cytogenetics in Oncology and Haematology 18: 938-940, 2014.
Ishii J, Sato H, Yazawa T, Shishido-Hara Y, Hiramatsu C, Nakatani Y, Kamma H: Class III/IV POU transcription factors expressed in small cell lung cancer cells are involved in proneural/neuroendocrine differentiation. Pathol Int 64: 415-422, 2014.
Endo T, Yazawa T, Shishido-Hara Y, Fujiwara M, Shimoyamada H, Ishii J, Sato H, Tachibana K, Takei H, Kondo H, Goya T, Endo S, Kamma H: Expression of developing neural transcription factors in lung carcinoid tumors. Pathol Int 64: 365-374, 2014.
Shishido-Hara Y, Yazawa T, Nagane M, Higuchi K, Abe-Suzuki S, Kurata M, Kitagawa M, Kamma H, Uchihara T: JC virus inclusions in progressive multifocal leukoencephalopathy: scaffolding promyelocytic leukemia nuclear bodies grow with cell cycle transition through an S-to-G2-like state in enlarging oligodendrocyte nuclei. J Neuropathol Exp Neurol 73: 442-453, 2014.
Iwasawa T, Ogura T, Sakai F, Kanauchi T, Komagata T, Baba T, Gotoh T, Morita S, Yazawa T, Inoue T: CT analysis of the effect of pirfenidone in patients with idiopathic pulmonary fibrosis. Eur J Radiol 83: 32-38, 2014.

2013

Ishii J, Sato H, Sakaeda M, Shishido-Hara Y, Hiramatsu C, Kamma H, Shimoyamada H, Fujiwara M, Endo T, Aoki I, Yazawa T: POU domain transcription factor BRN2 is crucial for expression of ASCL1, ND1, and neuroendocrine marker molecules and cell growth in small cell lung cancer. Pathol Int 63: 158-168, 2013.
Sakaeda M, Sato H, Ishii J, Miyata C, Kamma H, Shishido-Hara Y, Shimoyamada H, Fujiwara M, Endo T, Tanaka R, Kondo H, Goya T, Aoki I, Yazawa T: Neural lineage-specific homeoprotein BRN2 is directly involved in TTF1 expression in small-cell lung cancer. Lab Invest 93: 408-421, 2013.

2012

Kashiwagi K, Ishii J, Sakaeda M, Arimasu Y, Shimoyamada H, Sato H, Miyata C, Kamma H, Aoki I, Yazawa T: Differences of molecular expression mechanisms among neural cell adhesion molecule 1, synaptophysin, and chromogranin A in lung cancer cells. Pathol Int 62: 232-245, 2012.
Matsushita K, Kanna M, Yazawa T, Shimizu S, Nitta M, Takamizawa T, Arakawa K, Yano H, Nishikawa M, Himeno H: Long-term survivor with pulmonary veno-occlusive disease. Circulation 125: e503-506, 2012.

2011

Sakamoto S, Yazawa T, Baba Y, Sato H, Kanegae Y, Hirai T, Saito I, Goto T, Kurahashi K: Keratinocyte growth factor gene transduction ameliorates pulmonary fibrosis induced by bleomycin in mice. Am J Respir Cell Mol Biol 45: 489-497, 2011.
Sato H, Sakaeda M, Ishii J, Kashiwagi K, Shimoyamada H, Okudela K, Tajiri M, Ohmori T, Ogura T, Woo T, Masuda M, Hirata K, Kitamura H, Yazawa T: Insulin-like growth factor binding protein-4 gene silencing in lung adenocarcinomas. Pathol Int 61: 19-27, 2011.
Kashiwagi K, Virgona N, Yamada J, Sato A, Ota M, Yazawa T, Yano T: Bowman-Birk protease inhibitor from soybeans enhances cisplatin-induced cytotoxicity in human mesothelioma cells. Exp Ther Med 2: 719-724, 2011.

2010

Shimoyamada H, Yazawa T, Sato H, Okudela K, Ishii J, Sakaeda M, Kashiwagi K, Suzuki T, Mitsui H, Woo T, Tajiri M, Ohmori T, Ogura T, Masuda M, Oshiro H, Kitamura H: Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells. Am J Pathol 177: 70-83, 2010.
Iwasawa T, Ogura T, Takahashi H, Asakura A, Gotoh T, Yazawa T, Inoue T: Pneumothorax and idiopathic pulmonary fibrosis. Jpn J Radiol 28: 672-679, 2010.
Woo T, Okudela K, Mitsui H, Yazawa T, Ogawa N, Tajiri M, Yamamoto T, Rino Y, Kitamura H, Masuda M: Prognostic value of CD133 expression in stage I lung adenocarcinomas. Int J Clin Exp Pathol 4: 32-42, 2010.
Okudela K, Woo T, Mitsui H, Yazawa T, Shimoyamada H, Tajiri M, Ogawa N, Masuda M, Kitamura H: Proposal of an improved histological sub-typing system for lung adenocarcinoma – significant prognostic values for stage I disease. Int J Clin Exp Pathol 3: 348-366, 2010.
Otsu K, Toya Y, Oshikawa J, Kurotani R, Yazawa T, Sato M, Yokoyama U, Umemura S, Minamisawa S, Ishikawa Y: Caveolin gene transfer improves glucose metabolism in diabetic mice. Am J Physiol Cell Physiol 298: C450-456, 2010.
Okudela K, Woo T, Mitsui H, Yazawa T, Shimoyamada H, Tajiri M, Ogawa N, Masuda M, Kitamura H: Morphometric profiling of lung cancers – its association with clinicopathologic, biologic, and molecular genetic features. Am J Surg Pathol 34: 243-255, 2010.
Sawahata M, Ogura T, Tagawa A, Takahashi H, Yazawa T, Matsuura M, Takemura T: Sauropus androgynous-associated bronchiolitis obliterans of mother and daughter – autopsy report. Respir Med CME 3: 214-217, 2010.
Suzuki K, Takahashi H, Abe Y, Inamori M, Watanabe S, Koide T, Tokoro C, Iida H, Hosono K, Endo H, Shimamura T, Kobayashi N, Kirikoshi H, Kubota K, Saito S, Ono H, Akiyama H, Yazawa T, Nakajima A: A case of a peculiarly shaped gastrointestinal stromal tumor. Endoscopy 42 Suppl 2: E65-66, 2010.
Okudela K, Yazawa T, Tajiri M, Omori T, Takahashi K, Woo T, Shimoyamada H, Ogawa N, Kitamura H: A case of epithelial-myoepithelial carcinoma of the bronchus - A review of reported cases and a comparison with other salivary gland-type carcinomas of the bronchus. Pathol Res Pract 206: 121-129, 2010.

2009

Yazawa T, Sato H, Shimoyamada H, Okudela K, Woo T, Tajiri M, Ogura T, Ogawa N, Suzuki T, Mitsui H, Ishii J, Miyata C, Sakaeda M, Goto K, Kashiwagi K, Masuda M, Takahashi T, Kitamura H: Neuroendocrine cancer-specific up-regulating mechanism of insulin-like growth factor binding protein-2 in small cell lung cancer. Am J Pathol 175: 976-987, 2009.
Okudela K, Yazawa T, Ishii J, Woo T, Mitsui H, Bunai T, Sakaeda M, Shimoyamada H, Sato H, Tajiri M, Ogawa N, Masuda M, Sugimura H, Kitamura H: Down-regulation of FXYD3 expression in human lung cancers: its mechanism and potential role in carcinogenesis. Am J Pathol 175: 2646-2656, 2009.
Okudela K, Yazawa T, Woo T, Sakaeda M, Ishii J, Matsui H, Shimoyamada H, Sato H, Tajiri M, Ogawa N, Masuda M, Takahashi T, Sugimura H, Kitamura H: Down-regulation of DUSP6 expression in lung cancer: its mechanism and potential role in carcinogenesis. Am J Pathol 175: 867-881, 2009.
Iwasawa T, Asakura A, Sakai F, Kanauchi T, Gotoh T, Ogura T, Yazawa T, Nishimura J, Inoue T: Assessment of prognosis of patients with idiopathic pulmonary fibrosis by computer-aided analysis of CT images. J Thorac Imaging 24: 216-222, 2009.
Kitamura H, Okudela K, Yazawa T, Sato H, Shimoyamada H: Cancer stem cell: implications in cancer biology and therapy with special reference to lung cancer. Lung Cancer 66: 275-281, 2009.
Kitamura H, Yazawa T, Sato H, Okudela K, Shimoyamada H: Small cell lung cancer: significance of RB alterations and TTF1 expression in its carcinogenesis, phenotype and biology. Endocr Pathol 20: 101-107, 2009.
Okudela K, Woo T, Yazawa T, Ogawa N, Tajiri M, Masuda M, Kitamura H: Significant association between EGFR-mutated lung adenocarcinoma and past illness from gastric cancer or uterine myoma: its implication in carcinogenesis. Lung Cancer 66: 287-291, 2009.
Woo T, Okudela K, Yazawa T, Wada N, Ogawa N, Ishiwa N, Tajiri M, Rino Y, Kitamura H, Masuda M: Prognostic value of KRAS mutations and Ki-67 expression in stage I lung adenocarcinomas. Lung Cancer 65: 355-362, 2009.
Okudela K, Yazawa T, Suzuki T, Sugimura H, Kitamura H: Role of 3’-phosphoinositides in oncogenic KRAS-induced modulation of shape and motility of airway epithelial cells. Pathol Int 59: 28-37, 2009.
Ohta S, Uemura H, Matsui Y, Ishiguro H, Fujinami K, Kondo K, Miyamoto H, Yazawa T, Danenberg K, Danenberg PV, Tohnai I, Kubota Y: Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107: 81-91, 2009.
Kashiwagi K, Virgona N, Harada K, Kido W, Yano Y, Ando A, Hagiwara K, Yano T: A redox-silent analogue of tocotrienol acts as a potential cytotoxic agent against human mesothelioma cells. Life Sci 84: 650-656, 2009.

2008以前

Shimato S, Natsume A, Wakabayashi T, Tsujimura K, Nakahara N, Ishii J, Ito M, Akatsuka Y, Kuzushima K, Yoshida J. Identification of a human leukocyte antigen-A24-restricted T-cell epitope derived from interleukin-13 receptor alpha2 chain, a glioma-associated antigen. J Neurosurg 109: 117-122, 2008.
Kitamura H, Yazawa T, Okudela K, Shimoyamada H, Sato H: Molecular and genetic pathogenesis of lung cancer: differences between small-cell and non-small-cell carcinomas. Open Pathol J 2: 106-114, 2008.
Kashiwagi K, Harada K, Yano Y, Kumadaki I, Hagiwara K, Takebayashi J, Kido W, Virgona N, Yano T: A redox-silent analogue of tocotrienol inhibits hypoxic adaptation of lung cancer cells. Biochem Biophys Res Commun 365: 875-881, 2008.
Ota S, Nakamura K, Yazawa T, Kawaguchi Y, Baba Y, Kitaoka R, Morimura N, Goto T, Yamada Y, Kurahashi K: High tidal volume ventilation induces lung injury after hepatic ischemia-reperfusion. Am J Physiol Lung Cell Mol Physiol 292: L625-631, 2007.
Imai N, Hashimoto T, Kihara M, Yoshida S, Kawana I, Yazawa T, Kitamura H, Umemura S: Roles for host and tumor angiotensin II type 1 receptor in tumor growth and tumor-associated angiogenesis. Lab Invest 87: 189-198, 2007.
Baba Y, Yazawa T, Kanegae Y, Sakamoto S, Saito I, Morimura N, Goto T, Yamada Y, Kurahashi K: Keratinocyte growth factor gene transduction ameliorates acute lung injury and mortality in mice. Hum Gene Ther 18: 130-141, 2007.
Hashimoto T, Kihara M, Imai N, Yoshida S, Shimoyamada H, Yasuzaki H, Ishida J, Toya Y, Kiuchi Y, Hirawa N, Tamura K, Yazawa T, Kitamura H, Fukamizu A, Umemura S: Requirement of apelin-apelin receptor system for oxidative stress-linked atherosclerosis. Am J Pathol 171: 1705-1712, 2007.
Takeuchi H, Natsume A, Wakabayashi T, Aoshima C, Shimato S, Ito M, Ishii J, Maeda Y, Hara M, Kim SU, Yoshida J. Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner. Neurosci Lett 426: 69-74, 2007.
Ishii J, Natsume A, Wakabayashi T, Takeuchi H, Hasegawa H, Kim SU, Yoshida J. The free-radical scavenger edaravone restores the differentiation of human neural precursor cells after radiation-induced oxidative stress. Neurosci Lett 423: 225-230, 2007.
Saito T, Sato H, Virgona N, Hagiwara H, Kashiwagi K, Suzuki K, Asano R, Yano T: Negative growth control of osteosarcoma cell by Bowman-Birk protease inhibitor from soybean; involvement of connexin 43. Cancer Lett 253: 249-257, 2007.
Sato H, Yazawa T, Suzuki T, Shimoyamada H, Okudela K, Ikeda M, Hamada K, Yamada-Okabe H, Yao M, Kubota Y, Takahashi T, Kamma H, Kitamura H: Growth regulation via insulin-like growth factor binding protein-4 and -2 in association with mutant K-ras in lung epithelia. Am J Pathol 169: 1550-1566, 2006.
Inayama Y, Hanashi M, Yazawa T, Mitsui H, Kimura A, Ito D: Massive gliosis of the retina: report of a case investigated by immunohistochemistry and clonality assays. Hum Pathol 36: 702-705, 2005.
Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H: PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell 37: 25-35, 2005.
Okudela K, Hayashi H, Ito T, Yazawa T, Suzuki T, Nakane Y, Sato H, Ishii H, KeQin X, Masuda A, Takahashi T, Kitamura H: K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via AKT activation: possible contribution to non-invasive expansion of lung adenocarcinoma. Am J Pathol 164: 91-100, 2004.
Kurahashi K, Ota S, Nakamura K, Nagashima Y, Yazawa T, Satoh M, Fujita A, Kamiya R, Fujita E, Baba Y, Uchida K, Morimura N, Andoh Y, Yamada Y: Effect of lung-protective ventilation on severe Pseudomonas aeruginosa pneumonia and sepsis in rats. Am J Physiol Lung Cell Mol Physiol 287: 402-410, 2004.
Ishii H, Yazawa T, Sato H, Suzuki T, Ikeda M, Hayashi Y, Takanashi T, Kitamura H: Enhancement of pleural dissemination and lymph node metastasis of intrathoracic lung cancer cells by vascular endothelial growth factors (VEGFs). Lung Cancer 45: 325-337, 2004.
Nagai J, Yazawa T, Okudela K, Kigasawa H, Kitamura H, Osaka H: Retinoic acid induces neuroblastoma cell death by inhibiting proteasomal degradation of retinoic acid receptor alpha. Cancer Res 64: 7910-7917, 2004.
van den Elsen PJ, van der Stoep N, Yazawa T: Class II transactivator (CIITA) deficiency in tumor cells: complicated mechanisms or not? Correspondence and author’s reply. Am J Pathol 163: 373-376, 2003.
Ishiwa N, Ogawa N, Shoji A, Maehara T, Hayashi Y, Takanashi Y, Yazawa T, Ito T: Correlation between lymph node micrometastasis and histologic classification of small lung adenocarcinomas, in considering the indication of limited surgery. Lung Cancer 39: 159-164, 2003.
Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H: Mechanisms of neuroendocrine differentiation in pulmonary neuroendocrine cells and small cell carcinoma. Endocr Pathol 14: 133-139, 2003.
Yazawa T, Ishii H, Ito T, Yoshiike Y, Ogawa N, Okudela K, Hayashi H, Suzuki T, Mitsui H, Ikeda M, Kitamura H: Colliding primary lung cancers of adenosquamous and large cell neuroendocrine carcinoma. Pathol Int 53: 58-65, 2003.
Yazawa T, Ito T, Kamma H, Suzuki T, Okudela K, Hayashi H, Horiguchi H, Ogata T, Mitsui H, Ikeda M, Kitamura H: Complicated mechanisms of class II transactivator transcription deficiency in small cell lung cancer and neuroblastoma. Am J Pathol 161: 291-300, 2002.
Ito T, Ogura T, Ogawa N, Udaka N, Hayashi H, Inayama Y, Yazawa T, Kitamura H: Modulation of pulmonary neuroendocrine cells in idiopathic interstitial pneumonia. Histol Histopathol 17: 1121-1127, 2002.
Hayashi H, Yazawa T, Okudela K, Nagai J, Ito T, Kanisawa M, Kitamura H: Inactivation of O⁶-methylguanine-DNA methyltransferase in human lung adenocarcinoma relates to high-grade histology and worse prognosis among smokers. Cancer Science 93: 184-189, 2002.
Hirota M, Ito T, Okudela K, Kawabe R, Yazawa T, Hayashi H, Nakatani Y, Fujita K, Kitamura H: Cell proliferation activity and the expression of cell cycle regulatory proteins in oral lichen planus. J Oral Pathol Med 31: 204-212, 2002.
Ito T, Udaka N, Ikeda M, Yazawa T, Kageyama R, Kitamura H: Significance of proneural basic helix-loop-helix transcription factors in neuroendocrine differentiation of fetal lung epithelial cells and lung carcinoma cells. Histol Histopathol 16: 335-343, 2001.
Hirota M, Ito T, Okudela K, Kawabe R, Hayashi H, Yazawa T, Fujita H, Kitamura H: Expression of cyclin dependent kinase inhibitors in taste buds of mouse and hamster. Tissue Cell 33: 25-32, 2001.
Ito T, Udaka N, Ikeda M, Yazawa T, Kageyama R, Kitamura H: Significance of proneural basic helix-loop-helix transcription factors in neuroendocrine differentiation of fetal lung epithelial cells and lung carcinoma cells. Histol Histopathol 16:335-343, 2001.
Hayashi H, Ogawa N, Ishiwa N, Yazawa T, Inayama Y, Ito T, Kitamura H: High cyclin E and low p27/Kip1 expressions are potentially poor prognostic factors in lung adenocarcinoma patients. Lung Cancer 34: 59-65, 2001.
Ikoma T, Ito T, Okudela K, Hayashi H, Yazawa T, Kitamura H: Modulation of expression of Cip/Kip family of cyclin dependent kinase inhibitors in foetal developing lungs of hamsters. Cell Prolif 34: 233-241, 2001.
Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H: Basic helix-loop-helix factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development 127: 3913-3921, 2000.
Hayashi H, Ito T, Yazawa T, Ikeda M, Inayama Y, Nakatani Y, Kameda Y, Nakamura N, Kitamura H: Reduced expression of p27/Kip1 is associated with the development of pulmonary adenocarcinoma. J Pathol 192: 26-31, 2000.
Ohtsuka M, Satoh H, Inoue M, Yazawa T, Yamashita YT, Sekizawa K, Hasegawa S: Disseminated metastasis of neuroblastomatous component in immature mediastinal teratoma: a case report. Anticancer Res 20: 527-530, 2000.
Yazawa T, Kamma H, Fujiwara M, Matsui M, Hiriguchi H, Satoh H, Fujimoto M, Yokoyama K, Ogata T: Lack of class II transactivator causes severe deficiency in HLA-DR expression in small cell lung cancer. J Pathol 187: 191-199, 1999.
Kamma H, Wan L, Horiguchi H, Matsui M, Fujiwara M, Fujimoto M, Yazawa T, Dreyfuss G: Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms. Exp Cell Res 246: 399-411, 1999.
Morishima Y, Satoh H, Ohtsuka M, Yazawa T, Yamashita Y, Hasegawa S: Primary mediastinal nonseminomatous germ cell tumor in an adult female. Respir Med 92: 882-884, 1998.
Satoh H, Ishikawa H, Fujimoto M, Fujiwara M, Yamashita YT, Yazawa T, Ohtsuka M, Hasegawa S, Kamma H: Angiocytotoxic therapy in human non-small cell lung cancer cell lines: advantage of combined effects of TNP-470 and SN-38. Acta Oncol 37: 85-90, 1998.
Fujiwara M, Satoh H, Fujimoto M, Yazawa T, Ishikawa H, Horiguchi H, Ogata T, Matsui M, Kamma H: Lung cancer cell line producing cytokeratin 19 fragment and sialyl Lewis X-I antigen. Anticancer Res 18: 1043-1046, 1998.
Satoh H, Ishikawa H, Fujimoto M, Fujiwara M, Yamashita YT, Yazawa T, Ohtsuka M, Hasegawa S, Kamma H: Combined effects of TNP-470 and taxol in human non-small cell lung cancer cell lines. Anticancer Res 18: 1027-1030, 1998.
Ishikawa H, Satoh H, Hasegawa S, Yazawa T, Naito T, Yamashita YT, Ohtsuka M, Ogata T, Kamma H: Urokinase-type plasminogen activator in carcinomatous pleural fluid. Eur Respir J 10: 1566-1571, 1997.
Satoh H, Ishikawa H, Funayama Y, Yazawa T, Ogata T, Hasegawa S: Combination cytotoxic effects of 5-fluorouracil and carboplatin against human lung cancer cell lines. Cancer Res Ther Control 4: 199-202, 1995.
Terada Y, Mitsui T, Yazawa T: Histologic evaluation of coronary exposure using an ultrasonic surgical aspirator. Ann Thorac Surg 57: 1054-1055, 1994.
Hamano K, Tsukamoto H, Yazawa T, Yoshimura M, Takita H: Infantile progressive muscular atrophy with ophthalmoplegia and pyramidal symptoms. Pediatr Neurol 10: 320-324, 1994.
Satoh H, Yano H, Yazawa T, Hasegawa S: Successful pregnancy after curative therapy for advanced lung cancer. Chest 105: 307-308, 1994.
Yazawa T, Kamma H, Ogata T: Frequent expression of HLA-DR antigen in medullary carcinoma of the breast. A possible reason for its prominent lymphocytic infiltration and favorable prognosis. Appl Immunohistochem Mol Morphol (formerly Appl Immunohistochem) 1: 289-296, 1993.
Yazawa T, Kamma H, Ogata T: HLA-DR antigen expression and lymphoid stromal reaction of breast cancer. Ann Cancer Res Ther 2: 123-124, 1993.
Yamamoto T, Yazawa T, Ogata T, Akaogi E, Mitsui K: Clear cell carcinoma of the lung: a case report and review of the literature. Lung Cancer 10: 101-106, 1993.
Iijima T, Doi M, Kamma H, Horiguchi H, Yazawa T, Ogata T: Pulmonary vasculature in idiopathic dilated cardiomyopathy. Acta Pathol Jap 43: 28-35, 1993.
Kamma H, Yazawa T, Ogata T: Expression of MHC class II antigens in human lung cancer cells. Virchows Arch B Cell Pathol Incl Mol Pathol 60: 407-412, 1991.
Yazawa T, Ogata T, Kamma H, Sibagaki T, Iijima T, Horiguchi H: Pulmonary blastoma with a topographic transition from blastic to more differentiated areas. An immunohistochemical assessment of its embryonic nature using stage-specific embryonic antigens. Virchows Arch A Pathol Anat Histopathol 419: 513-518, 1991.